Central Neuronal Histamine Contributes to Cardiovascular Regulation.

نویسنده

  • Steven L. Bealer
چکیده

Evidence suggests that central histaminergic neurons make important contributions to cardiovascular regulation. For example, histamine-containing neurons project to brain regions important for cardiovascular regulation. Furthermore, stimulation of central histamine receptors changes blood pressure and heart rate and alters activity of major vasoconstrictor systems. Finally, histamine metabolism is changed in hypertension.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Central effect of histamine and peripheral effect of histidine on food intake in rabbits

Histidine is an amino acid precursor of neuronal histamine. It is evident that peripheral injection of histidine produces effects that resemble to centrally administered histamine. The aim of the present study was to compare the effects of intracerebroventricular (ICV) injection of histamine and inraperitoneal (IP) injection of histidine on food intake in rabbits. ICV injections of histamine (1...

متن کامل

Central effect of histamine and peripheral effect of histidine on food intake in rabbits

Histidine is an amino acid precursor of neuronal histamine. It is evident that peripheral injection of histidine produces effects that resemble to centrally administered histamine. The aim of the present study was to compare the effects of intracerebroventricular (ICV) injection of histamine and inraperitoneal (IP) injection of histidine on food intake in rabbits. ICV injections of histamine (1...

متن کامل

P185: Survey Effect of Histamine on Microglia in Neurodegenerative Diseases

Neurodegenerative diseases contain Multiple Sclerosis (MS), Alzheimer’s disease (AD) and Parkinson’s disease (PD), are characterized by neuronal death and neuronal degeneration in specific regions of the central nervous system (CNS). Microglia are the basic immune brain cells and play a role in homeostasis after inflammation challenge. Microglia involves in Neurodegenerative disease...

متن کامل

Influence of SKF 91488, histamine N-methyltransferase inhibitor, on the central cardiovascular regulation during controlled, stepwise hemorrhagic hypotension in rats.

The histaminergic system influences various activities of the central nervous system, including cardiovascular regulation. Histamine administered intracerebroventricularly (i.c.v.) in anesthetized rats produces the increase in mean arterial pressure (MAP) and heart rate (HR), however, in contrast to normotensive animals, histamine-induced rises in MAP and HR in critically hypotensive animals ar...

متن کامل

Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian hamster.

Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage. Little is known, however, of the hypothalamic neuronal events that lead to a change in behavior or physiology. Here we show for the first time that a shift ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society

دوره 14  شماره 

صفحات  -

تاریخ انتشار 1999